Daulatkhan upazila on the north, Lalmohan and Manpura upazilas on the south, Hatiya upazila on the east, Burhanuddin upazila on the west.

Tazumuddin thana was turn into an upazila in 1983. The upazila consists of 5 union parishads, 16 mouzas and 62 villages.

Tazumuddin Upazila is located in Bhola District. Upazilla(s)/Thana(s) in Bhola are Bhola Sadar Upazila, Burhanuddin Upazila, Charfasson Upazila, Daulatkhan Upazila, Lalmohan Upazila, Manpura Upazila, Tazumuddin Upazila.